QUANTI-HLAb: An In Vitro Diagnostic Kit for transplant recipients

DESCRIPTION

  • Innovative technology based on Surface Plasmon Resonance (SPR) in a capture mode,
  • Access to HLA antibodies’ active concentration and affinity,
  • Active concentration (high capture level) and affinity (low capture level) of several sample/HLA targets can be performed on the same chip.

INVENTORS

Jonathan VISENTIN
Jean-Luc TAUPIN
Immunology from concept and experiments to translation (ImmunoConcEpT, UMR 5164)

CONTACT

Nom : Lucile Tran,
Titre : Chef de Projet Santé,
Mail : l.tran@ast-innovations.com

APPLICATIONS

  • Diagnostic kit for organ transplantation
  • Identification of HLA antibodies parameters
  • Evaluation of HLA antibodies pathogenicity
  • Prevention of transplant rejection
  • Follow-up of humoral rejection therapies

BENEFITS

  • Determination of quantitative parameters for HLA antibodies in patient samples
  • No calibration curve and reusable chip
  • Real-time and label-free assay
  • To anticipate clinical outcomes for organ recipients
  • To facilitate clinical decision

IP

This technology is protected by a patent application

MATURATION

Proof of concept established on a cohort of lung transplant recipients

By | 2017-04-21T12:36:36+00:00 avril 4th, 2017|