About Lucile Tran

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So far Lucile Tran has created 5 blog entries.

INDEME: A targeted approach for depigmentation disorders

Identification of a core molecule X1 involved in melanocytes detachment responsible for depigmentation in vitiligo and post-inflammatory skin disorders Ex vivo analysis −Higher X1 expression in vitiligo patients’ skin and sera compared to healthy subjects −Vitiligo patients: Positive correlation between X1 level and the body surface area involved POC in vitro: −Inhibitors targeting X1 prevent melanocyte detachment in a 3D-induced depigmentation model

By | 2018-02-08T17:18:03+00:00 avril 21st, 2017|

Lymphoma Mouse Model: a useful model for rapid biological and therapeutic evaluation

Original method of intrahepatic injection of CTCL into adult immunodeficient mice Engraftment validated with aggressive (My-La, HUT78, HH, MAC2A, MAC2B) and indolent (FE-PD, MAC1) CTCL cell lines, DLBCL cell line (HLY1) and patient-derived CTCL xenograft Migration and cell spreading assessment in blood, kidneys, lungs, spleen … Model validation with methotrexate as positive drug control treatment

By | 2018-02-08T17:33:05+00:00 avril 21st, 2017|

QUANTI-HLAb: An In Vitro Diagnostic Kit for transplant recipients

Innovative technology based on Surface Plasmon Resonance (SPR) in a capture mode, Access to HLA antibodies’ active concentration and affinity, Active concentration (high capture level) and affinity (low capture level) of several sample/HLA targets can be performed on the same chip.

By | 2018-02-08T17:35:03+00:00 avril 4th, 2017|