TYPEBRETT: Determination of sulphite resistant strains of Brettanomyces DESCRIPTION This tools is easy handling and fast. It consists of a PCR reaction, followed [...]
UNIVERSLIDE: A versatile imaging chamber to observe biological samples in 3D/4D – suitable for all kinds of microscopes
Chamber frame designed to receive a coverslip (optical access from the bottom) Clip-on PDMS gasket to guarantee the system tightness Agarose substrate with an array of little wells Upper lid with second glass coverslip to seal the device and to provide optical access from top No stress nor strain on the sample, to guarantee the sample integrity
The 5 strains followed the same selection procedure : Adhesion test on glass tube: verification of the production of exopolysaccharides confirming that the bacteria can adhere to hard tissues, Hydrophobicity test, Co-aggregation test with bacteria responsible for periodontal disease and halitosis, Test of antibacterial activity against potentially pathogenic strains in the oral cavity, Saliva survival test: resistance and stability of probiotic candidates in the salivary environment. Safety Test: Verification that strains do not produce compounds responsible for bad breath, Immunogenicity test to understand the local immune response.
FibroCOPD: Drug repurposing for the treatment of chronic obstructive pulmonary disease (COPD) DESCRIPTION An increase in the level of circulating fibrocytes is found [...]
Repurposing molecule improving symptoms associated with obstructive cardiopathies and especially hypertrophic cardiomyopathy: exercise breathlessness exercise chest pain exercise discomfort exercise dizziness Validation with a first serie of human obstructive heart diseases Reduction of symptoms at rest or during effort Immediate decrease of intraventricular obstruction and hyperkinetic state Ongoing phase II clinical study on 40 patients
Présentation de la technologie Photo credit : net_efekt / Foter / CC BY Notre technologie concerne une signature moléculaire appliquée aux sarcomes qui sont des [...]
Présentation de la technologie La technologie repose sur un kit dont le but est de faire produire une molécule d’intérêt avec un rendement très élevé par une levure ayant intégré plusieurs [...]